There are few steps to enable SignalR into a web application. But how do this for a SharePoint based web application? 
The goal of this post is provide you a SharePoint deployment package to is automate such steps for a SharePoint web application.
The only thing you have to do is:
1) Download SignalR.SharePoint.wsp.
2) Install the SignalR distributed assemblies the web application bin directory from Powershell console:
>Add-PSSnapin Microsoft.SharePoint.PowerShell >Add-SPSolution (Resolve-Path .\SignalR.SharePoint.wsp) >Install-SPSolution SignalR.SharePoint.wsp -WebApplication $WebAppUrl -GACDeployment -FullTrustBinDeployment -Force
3) Enable [SignalR SharePoint Configuration Feature] - in the web application scope - in order to modify the web.config for run-time assembly binding redirection, set legacyCasModel to false (allow dynamic calls) and set the owin:AutomaticAppStartup application setting key to false.
...
   <trust level="Full" originUrl="" legacyCasModel="false" />
...
  <runtime>
    <assemblyBinding>
...
      <dependentAssembly>
        <assemblyIdentity name="Microsoft.Owin.Security" publicKeyToken="31bf3856ad364e35" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-2.1.0.0" newVersion="2.1.0.0" />
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="Microsoft.Owin" publicKeyToken="31bf3856ad364e35" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-2.1.0.0" newVersion="2.1.0.0" />
      </dependentAssembly>
      <dependentAssembly>
        <assemblyIdentity name="Newtonsoft.Json" publicKeyToken="30ad4fe6b2a6aeed" culture="neutral" />
        <bindingRedirect oldVersion="0.0.0.0-6.0.0.0" newVersion="6.0.0.0" />
      </dependentAssembly>
    </assemblyBinding>
  </runtime>
...
  <appSettings>
...
    <add key="owin:AutomaticAppStartup" value="false" />
  </appSettings>
4) Create and deploy your hub based assembly into the web application. The easy way to do this is by writing the hub in a SharePoint based project and set the “Assembly Deployment Target” to WebApplication. You can also try with this simple chat example by deploying it into your web application.
5) Enable the [SignalR SharePoint Enable AutomaticAppStartup Feature] - in the web application scope - in order turn the owin:AutomaticAppStartup application setting key to true.
  <appSettings>
...
    <add key="owin:AutomaticAppStartup" value="true" />
  </appSettings>
6) Just open your browser and navigates to the application page. If you deployed the chat example, you can try with %WebApplicationUrl%/_layouts/15/_layouts/15/SignalR.SharePoint.Demo/Chat.aspx application page. 
 
 
 
